Igor A. Grigor'ev

Professor, Director, Head of Laboratory of Nitrogen Compounds,Novosibirsk Institute of Organic Chemistry SB RAS
Professor, Head of Organic Chemistry Chair, Novosibirsk State University
Professor of Organic Chemistry Chair in Novosibirsk State Teachers’ University,
Born in 1948 in Khabarovsk, USSR
Education and scientific degree:
  • 1990 Doctor of Chemical Sciences (Doctor Nauk), Novosibirsk Institute of Organic Chemistry
  • 1980 PhD in Chemistry, Novosibirsk Institute of Organic Chemistry SB RAS
  • 1971 Graduated from Department of Chemistry, Novosibirsk State University

Professional appointments:
  • 2003 - now      - Head of Organic Chemistry Chair (Novosibirsk State University)
  • 2002 - now      - Director (Institute of Organic Chemistry, Novosibirsk)
  • 1997-2002     - Deputy Director (Institute of Organic Chemistry, Novosibirsk)
  • 1983-1977     - Senior Scientific Researcher (Institute of Organic Chemistry, Novosibirsk)
  • 1974-1983     - Junior Research Fellow (Institute of Organic Chemistry, Novosibirsk)
  • 1971-1973     - Postgraduate Fellow (Institute of Organic Chemistry, Novosibirsk)

Honours, Awards, Fellowships, Membership of Professional Societies:
  • 1994 – Russian Federation State Prize Winner in Science and Technology
  • Member of the American Chemical Society
  • Member of the Scientific Coordination Council of RAS on Organic and Elementoorganic Chemistry
  • Member of International EPR Society

Fields of scientific interest:
  • Organic chemistry, especially chemistry of the nitrogen containing heterocyclic compounds: nitrones, nitroxides, hydroxylamines; synthesis, analytical and biological applications of spin labels and traps
  • Analytical chemistry, Spectroscopy (NMR, ESR, IR, UV, Mass-spectrometry), electrochemistry

Publications (12 recent, in total about 170):
  1. Voinov M.A., Grigor’ev I.A., Volodarsky L.B.
    Dipole Stabilized Carbanions in series of Cyclic Aldonitrones. Part 1. Aldonitrones Metallation and Dimerization in LDA and n-BULi Solutions
    Heterocyclic Communications, 1998, Vol. 4, N 3, P.261-270.
  2. Voinov M.A., Grigor’ev I.A., Volodarsky L.B.
    Dipole-Stabilized Carbanions in series of Cyclic Aldonitrones. Part II. Reactions of the Metalated Aldonitrones – Derivatives of Imidazoline 3-Oxide and 2H-Imidazole 1-Oxide with Aldehydes and Ketones
    Tetrahedron, 2000 Vol. 56, P.4071-4077.
  3. Khramtsov V.V., Grigor’ev I.A., Foster M.A., Lurie D.J.
    Biological applications of spin pH-probes,
    Cellular and Molecular Biology, 2000, vol.46(8), P.1361-1374.
  4. Glazachev Yu.D., Grigor’ev I.A., Reijerse E.J., Khramtsov V.V.
    EPR Studies of 15-N- and 2-H-Substituted pH-Sensitive Spin Probes of Imidazoline Type
    Applied Magnetic Resonance, 2001, Vol.20, P.486-502.
  5. Voinov M.A., Salnikov G.E., Mamatyuk V.I., Shakirov M.M., Grigor’ev I.A.
    Dipole-Stabilized Carbanions in Series of Cyclic Aldonitrones. Part IV. 13-C, 14-N, and 7-Li NMR Spectra of Dipole-Stabilized Organolithiums derived from a cyclic aldonitrone
    Magn.Reson.Chem., 2001, Vol.39, p.681-683.
  6. Voinov M.A., Grigor’ev I.A.
    A Route to the Synthesis of Previously Unknown alpha-Heteroatom Substituted Nitrones
    Tetrahedron Lett., 2002, Vol.43, N 13, P.2445-2447.
  7. Foster M.A., Grigor’ev I.A., Lurie D.J., Khramtsov V.V., Calluma S.Ms., Panagietelis I., Hutchison J.M.S., Koptioug A.V., Nicolson I.
    In vivo Detection of a pH-Sensitive Nitroxide in the Rat Stomach by Low-field ESR-based Techniques
    Magn.Res.Medicine, 2003, V.49, p.558-567.
  8. Kirilyuk I.A., Shevelev T.G., Morozov D.A., Khromovskih E.L., Skuridin N.G., Khramtsov V.V., Grigor’ev I.A.
    Grignard Reagent Addition to 5-Alkylamino-4H-Imidazole 3-Oxides: Synthesis of New pH-sensitive Spin Probes
    Synthesis, 2003,N 6, pp.871-878.
  9. Molochnikov L.S., Kovalyova E.G., Grigor’ev I.A., Zagorodni A.A.
    Direct measuring of H+ activity inside cross-linked functional polymers
    J.Phys.Chem., B, 2004, V.108, pp.1302-1313.
  10. Khramtsov V.V., Grigor’ev I.A., Foster M.A., Lurie D.J.
    In vitro and in vivo measurement of pH- and thiols by EPR-based techniques,
    Antioxid.Redox Signal. , 2004, V.6, N 3, pp.667-676.
  11. Smirnov A.I., Ruuge A., Reznikov V.A., Voinov M.A., Grigor’ev I.A.
    Site-Directed Electrostatic Measurements with a Thiol-Specific pH-Sensitive Nitroxide: Differentiating Local pK and Polarity Effects by High-Field EPR
    J.Amer.Chem.Soc., 2004, vol.126, pp.8872-8873.
  12. Kirilyuk I.A., Bobko A.A., Grigor’ev I.A., Khramtsov V.V.
    Synthesis of the tetraethyl substituted pH-sensitive nitroxides of imidazoline series with enhanced stability towards reduction,
    Org.Biomol.Chem., 2004,vol.2, pp.1025-1030.