Vadim K. Khlestkin, Ph.D.

Born in 1973 in Aktjubinsk, USSR
Curriculum Vitae
Vadim K. Khlestkin was born in February 17, 1973 in Aktjubinsk, USSR. 1982 - 1989 - lived in Dzhambul (now - Taraz) - beautiful city among deserts, mountains and steppes of Kazakhstan. Juicy fruits, luxuriant animal world and three chemical plants conditioned on his enthusiasm for living world and chemistry.
In 1989 Vadim K. Khlestkin left for Novosibirsk to enter the Novosibirsk state university, Faculty of natural philosophy, chemical department. Siberian permafrost allowed him to remain well preserved and also to receive MSc degree in organic chemistry in 1994 (Synthesis and properties of 1,2-bis(methoxyamino)cycloalkanes).

Education and scientific degree:
  • 1994     Graduated from Department of Chemistry, Novosibirsk State University
  • 1998     Ph.D. (Chemistry), Novosibirsk Institute of Organic Chemistry

Professional appointments:
  • 2005-now     Senior researcher, Lab. of Nitrogen Compounds, Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences
  • 2001-2002    Scientific secretary assistant of Novosibirsk Institute of Organic Chemistry.
  • 1998-2004    Researcher, Lab. of Nitrogen Compounds, Novosibirsk Institut of Organic Chemistry, Siberian Branch of Russian Academy of Sciences.
  • 1995-1998    Post-graduate student of Novosibirsk Institute of Organic Chemistry,

Fields of scientific interest:
  • Organic hydroxylamine derivatives (oximes, nitrones, hydroxamic acids, heterocyclic N-oxides, etc). Synthesis, properties, biological activities, application in life and material science.
  • Nitroxides with cirtain properties (pH-sensitive, magnetic properties, etc).
  • Nitronyl nitroxides with nonlinear optic and magnetic properties.
  • Supramolecular chemistry of nitrogen compounds.
  • New methods and reagents in organic chemistry, search and elaboration methodology, application.

Honours, Awards, Fellowships
  • 2002–2003 - PhD fellowship, KULeuven, Belgium.
  • 2004 - Second prize, Samsung Young Scientist Day, April 26-27.

Publications in Referred Journals and Conference Proceedings:
  1. Khlestkin V.K., Reznikov V.A., Mazhukin D.G., Tikhonov A.Ya., Volodarsky L.B.
    Reaction of N-(1-cyano-1-methylethyl)-a-phenylnitrone with phenyl-, 2-pyridyl- and 2-thienylmagnesium bromides: a new approach to alkylaromatic a-hydroxylaminoketones
    Mendeleev Commun. 1996, N 5, P. 202-203.
  2. Khlestkin V.K., Mazhukin D.G., Tikhonov A.Ya., Bagryanskaya I.Yu., Gatilov Y.V., Utepbergenov D.I., Khramtsov V.V., Volodarsky L.B.
    Unexpected Transformation of 1,2-Bis(N-methoxy-N-nitrosoamino)cycloalkanes: First Synthesis of 4,5-Dihydro-1,2,3-triazole 2-Oxides
    Tetrahedron Lett., vol. 37, N 33, 1996, P. 5997-6000.
  3. Mazhukin D.G., Khlestkin V.K., Tikhonov A.Ya., Volodarsky L.B.
    Synthesis of 1,2-bis(methoxyamino)cycloalkanes from alicyclic 1,2-bis(hydroxylamines)
    Russ. Chem. Bull., 1996, N 4, P. 925-929.
    Sintez 1,2-bis(metoksiamino)tsikloalkanov iz alitsiklicheskikh 1,2-bis(gidroksilaminov)
    Izv. Akad. nauk, Ser. Khim., 1996, N 4, S. 925-929
  4. Bagryanskaya I.Yu., Rybalova T.V., Gatilov Yu.V., Khlestkin V.K., Mazhukin D.G.
    The first X-ray study of alkoxynitrosoamines.
    Acta Crystallographica. Section C, 1998, V. 54, ¹ 12, P. IUC 9800073.
  5. Tikhonov A.Ya., Mazhukin D.G., Grigor’eva L.N., Khlestkin V.K., Voinova N.N., Syropyatov B. Ya., Shirinkina S.S., Volodarsky L.B.
    Synthesis and Inhibitory Effect on Platelet Aggregation and Antihypertensive Activity of 1-Hydroxy-2,5-dihydro-1H-imidazole-2-carboxylic Acid 3-Oxides, 1,3-Dihydroxyimidazolidine-2-carboxylic Acids and 1,4-Dihydroxy-2,3-piperazinediones
    Arch. Pharmazie, 1999, v. 9, P. 305-308.
  6. Khlestkin V.K., Mazhukin D.G., Tikhonov A.Ya., Rybalova T.V., Bagryanskaya I.Yu., Gatilov Yu.V.
    Intramolecular Cyclization of 1,2-Bis(N-alkoxy-N-nitrosoamino)alkanes: the Unique Route to 4,5-Dihydro-1,2,3-triazole 2-Oxides.
    Synthesis., ¹ 5, 2000, p. 681-690.
  7. Khlestkin V.K., Tikhonov A.Ya.
    Synthesis of pyrimidine and 1,3-bishydroxylamine derivatives from enone Mannich base methiodides.
    HETEROCYCL COMMUN 8 (3): 249-254 2002
  8. Slyudkin O.P., Khlestkin V.K., Tikhonov A.Ya., et al.
    Palladium(II) complexes with 1,2-bis(alkoxyamine)s.
    RUSS J INORG CHEM+ 47 (1): 60-67 JAN 2002 (Rus).
  9. Burdukov A.B., Ikorskii V.N., Pervukhina N.V., et al.
    Synthesis, structure, and magnetic properties of the mixed-ligand complex of copper(II) hexafluoroacetylacetonate with the nitroxide 4-(2 '-pyridyl)-2,2,5,5-tetramethyl-3-imidazoline-1-oxyl.
    J STRUCT CHEM+ 43 (1): 176-179 JAN-FEB 2002 (Rus).
  10. Slyudkin O.P., Khlestkin V.K., Tikhonov A.Ya., Baidina I.A.
    Pt(II) Iodide Complexes with Hydroxylamine and cis-1,2-Bis(alkoxyamino)cyclohexanes.
    RUSS J INORG CHEM 48(10), 1480-1486 2003.
  11. Khlestkin V.K., Mazhukin D.G.
    Recent Advances in the Application of N,O-Dialkylhydroxylamines in Organic Chemistry, Review,
    CURRENT ORGANIC CHEMISTRY, 2003, 7, 967-993.
  12. Khlestkin V.K., Glazachev Y.I., Kokorin A.I., Kostyanovsky R.G.
    ESR study of stereochemistry in chiral nitroxide radical crystals.
    Mendeleev Communications, 2004, 6, 318-320.
  13. Slyudkin O.P., Khlestkin V.K., Tikhonov A.Ya., Naumov D.Yu.
    Bis- i trischelatnie kompleksnie soedineniya Pd(II) s cis-1,2-bis(alkoksiamino)tsiklogeksanami.
    Zh. Neorg. Khimii, 2004, 49(6), 948-952 (Rus).
  14. Ch. Zhou, V.K. Khlestkin, D. Braeken, K. De Keersmaecker, W. Laureyn, Y. Engelborghs, G. Borghs
    Solvent-Controlled Organization of Self-Assembled Polymeric Monolayers on Gold: An Easy Approach for the Construction of Protein Resistant Surfaces
    Langmuir, 21, 2005, p. 5988-5996
  15. Butakov V.V.,Khlestkin V.K., Mazhukin D.G.
    Formation of N,N'-dihydroxy- and N,N'-dimethoxy-1,4-diazepine derivatives in the reaction of 1,2-bis(hydroxyamines) and 1,2-bis(methoxyamine) with enone Mannich bases
    Mendeleev Communications, ¹ 4, V. 15, 2005, p.162-163.